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Skip to content Skip to search Skip to footer Otolaryngology–Head & Neck Surgery Open Menu Back Close Menu Search for: Search Close Search AboutAbout History Our Mission Giving Contact Us Patient CarePatient Care Appointments & LocationsAppointments & Locations Virtual visits Patient safety For Referring Physicians Facial Plastic and Reconstructive Surgery Physicians Ear & HearingEar & Hearing Acoustic Neuroma Appointments & Locations Acoustic Neuroma Experts Auditory Brainstem Implants Our physicians Vestibular Cochlear Implant ProgramCochlear Implant Program Cochlear Implants Explained Rehabilitation & Research Audiology General OtolaryngologyGeneral Otolaryngology Common Complaints Sleep Disturbance Salivary Gland Disorders Head and Neck CancerHead and Neck Cancer Meet the Head and Neck Cancer Team World Class Multidisciplinary Care Surgical Innovation Head and Neck Cancer Survivorship Head and Neck Cancer Research International Physician Observer Program in Head & Neck Surgery Nose and Sinus DiseaseNose and Sinus Disease Rhinology Allergy Pediatric OtolaryngologyPediatric Otolaryngology Patient Forms & Information Sleep Voice & AirwayVoice & Airway Voice & Airway Team What our patients say Skull base surgery Specialties EducationEducation Residency ProgramsResidency Programs A Taste of WashU ENT Clinical Residency Physician-Scientist Training ProgramPhysician-Scientist Training Program Physician-Scientist Supplemental Resident Quality of Life Current Residents Recent Residency Graduates Applying & InterviewingApplying & Interviewing Information for Residency Candidates Fellowship ProgramsFellowship Programs Advanced Head & Neck Surgical Oncology and Microvascular ReconstructionAdvanced Head & Neck Surgical Oncology and Microvascular Reconstruction Physician Observations Neurotology Facial Plastic & Reconstructive Surgery Pediatric Otolaryngology Medical StudentsMedical Students Predoctoral Training Program Diversity sub-internship Courses Research Opportunities Surgical Simulation Lab Program in Audiology and Communication Sciences Learning Environment Alumni ResearchResearch LaboratoriesLaboratories Puram LabPuram Lab Puram Lab Opportunities Puram Lab Team Puram Lab News Puram Lab Publications Puram Lab Research Projects Kim LabKim Lab Kim Lab Opportunities Kim Lab Team Kim Lab Research Projects Kim Lab Publications Kim Lab News Firszt LabFirszt Lab Firszt Lab Contacts Firszt Lab Team Sheets Lab Outcomes Research People News & EventsNews & Events Clinical Research Education and Statistics Training (CREST) Workshop 2024 Midwest Otolaryngology Simulation Training Special EventsSpecial Events Senturia Lectureship Spector Lectureship Shepard Lecture Ogura Lectureship Calendar Latest NewsLatest News Newsletter Inclusion & Diversity Open Search Puram Lab Team Sid Puram, MD, PhDAssistant Professor Dr. Puram joined the Department of Otolaryngology at Washington University in 2018. He is fellowship trained in head and neck surgery and microvascular reconstruction. He is also the recipient of numerous research awards. He is devoted to improving the lives of head and neck cancer patients through his clinical practice and research. Check out his biosketch to learn more about Dr. Puram. Dr. Puram grew up in Edina, Minnesota and received dual degrees (B.S.) in Biology and Neuroscience from the Massachusetts Institute of Technology in 2005. At MIT, he became interested in aspects of immunology and drug delivery, working in the laboratory of Dr. Robert Langer (Institute Professor) to develop novel pH-trigged polymer microspheres for the delivery of genetic vaccines. This experience sparked his interest in research, and he joined the Harvard Medical Scientist Training Program, where he completed his PhD studies in Neurobiology at Harvard Medical School under the guidance of Dr. Azad Bonni. His primary research focus was on understanding the proteins that drive dendrite growth and retraction in the mammalian neurons, with a specific focus on ubiquitin family pathways and centrosomal signaling. He also dedicated himself to studying the pathways that promote glioblastoma tumorigenesis, an incurable cancer of the brain. Following his MD-PhD, Dr. Puram began his training in Otolaryngology-Head and Neck Surgery at the Harvard/Massachusetts Eye and Ear Infirmary Program, where he completed his clinical training and a post-doctoral fellowship with Dr. Bradley Bernstein (Massachusetts General Hospital/Broad Institute). In Dr. Bernstein’s lab, he completed the first comprehensive single cell atlas of head and neck squamous cell carcinoma, a major human epithelial carcinoma. By analyzing matched primary tumors and metastastic lymph nodes, these analyses revealed important insights into head and neck cancer, including identification of a partial epithelial-to-mesenchymal program that may drive metastasis and invasion. Dr. Puram completed his clinical training with a fellowship at the James Cancer Center at Ohio State University in Head and Neck Surgery and Microvascular Reconstruction thereafter. He was appointed Assistant Professor in the Department of Otolaryngology – Head and Neck Surgery and Department of Genetics at Washington University School of Medicine. Dr. Puram has received numerous awards for his research and clinical work including the Jeffrey P. Harris, MD, PhD Chief Resident Research Award, Chief Resident Award for Excellence in Teaching, William Montgomery, Richard Belluci, and John Conley Triologic Society Resident Research Awards, American Academy of Otolaryngology-Head and Neck Surgery Resident CORE Grant, New England Otolaryngology Society Resident Research Award, and Leon Reznick Memorial Prize for Excellence in Research at Harvard Medical School, among others. Dr. Puram is passionate about improving the lives of head and neck cancer patients through his clinical practice and research endeavors. Tom Barrett, MDResident in otolaryngology Tom received his MD from the Icahn School of Medicine at Mount Sinai in New York City in 2018, graduating with a distinction in research. He joined the WashU otolaryngology residency as a member of the T32 Physician Scientist Training Program. He joined Dr. Puram’s lab in the Summer of 2020 for two years of dedicated research time. He strives to improve the lives of patients with head and neck cancer both in the lab and at the bedside. Robert Crowder, PhDStaff scientist Bob earned his PhD in Pharmacology at the University of Rochester studying NGF-dependent cell survival signaling. He then pursued post-doctoral studies at Washington University in St. Louis. He has spent the past decade conducting oncology research and developing novel therapeutic approaches to improve outcomes in breast cancer patients. He joined the Puram lab in 2019. Yi-HSuan ChangGraduate student Yi-Hsuan grew up in Taipei, Taiwan, where he completed bachelor’s and master’s degrees at National Taiwan University. He came to St. Louis in the summer of 2019 to start his PhD studies in Molecular Cell Biology. He is interested in studying the underlyhing mechanisms for HNSCC progression in order to identify potential therapeutic targets. Outside of the lab, he enjoys reading novels, watching TV shows, and playing board games. Marina NogueiraGraduate student Marina is an MD/PhD student at Washington University in St. Louis studying transcriptional regulation by p63 in head and neck squamous cell carcinoma. She grew up in Santa Cruz, California and studied molecular biology and neuroscience at Princeton University. Outside of the lab, she enjoys swimming, cycling, and trying to taste all the ice cream in St. Louis.  Reilly (Alex) SamplePredoctoral research scholar Reilly (Alex) Sample is a visiting pre-doctoral research fellow who is currently between his 3rd and 4th years of medical school at UT Southwestern. His research interests include cancer biology, HPV, genetics, and health outcomes. He is currently pursuing a Master’s degree in clinical investigation through a TL1 grant from the NIH. He enjoys running, cycling, backpacking, and reading. Fudong Wang, PhDLab manager, Staff scientist Fudong received his Ph.D. degree in chemistry from Washington University. He is the lab manager. His research focuses on characterizing epigenetic and transcriptomic heterogeneity in head and neck cancers and understanding the mechanisms that underlie their growth, development, and spread using single cell technologies. Hobbies: sports, hiking, reading, and photography. Research Laboratories Puram Lab Kim Lab Firszt Lab Sheets Lab Outcomes Research Department of OtolaryngologyWashington University School of Medicine660 South Euclid AvenueCampus Box 8115St. Louis, MO [email protected] Us Instagram Twitter YouTube Contacts Physician directory MyChart Appointments: 314-362-7509 Administrative office: 314-362-7395 Media assistance Careers Faculty Job Openings Staff Job Openings Team Resources AMiON (Call Schedule) Workday ©2024 Washington University in St. Louis

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