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Skip to content Skip to search Skip to footer Ophthalmology & Visual Sciences Open Menu Back Close Menu Search for: Search Close Search Home About UsAbout Us Latest News and Announcements Faculty Directory History Becker Collection EducationEducation Residency ProgramResidency Program Meet the Residents What Distinguishes Us? 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Apte, MD, PhD, (right), of Washington University School of Medicine in St. Louis, examines patient Patricia Collins (left) while medical student Wilson Wang observes. Collins is a participant in a clinical trial that tests the safety and efficacy of an FDA-approved drug in stabilizing vision in patients with RVCL-S, a rare genetic […] Dr. Yoshimatsu Receives Seed Grant from Brain Research Foundation for Groundbreaking Zebrafish Visual Attention Study June 6, 2024June 7, 2024 We are thrilled to announce that Dr. Yoshimatsu has been awarded a prestigious two-year seed grant from the Brain Research Foundation for his innovative research titled “Zebrafish Model to Study Visual Attention.” This grant will support pioneering work aimed at understanding the genetic mechanisms underlying visual attention, with profound implications for neurodevelopmental disorders such as […] Medical Student Wilson Wang and Resident Maggie Xing Publish Key Article on Proliferative Vitreoretinopathy in JAMA Ophthalmology May 24, 2024June 12, 2024 Medical student Wilson Wang and resident physician Maggie Xing, MD, have made significant contributions to the field of ophthalmology with their recent publication in JAMA Ophthalmology “Interventions for Proliferative Vitreoretinopathy,” co-authored with renowned expert Raj Apte, MD, PhD. Their article provides a comprehensive clinical synopsis and educational review of proliferative vitreoretinopathy (PVR), a serious complication […] Exploring Retinal Biomarkers in Huntington Disease: A Groundbreaking Study May 24, 2024May 29, 2024 In a significant leap forward for neurodegenerative disease research, Retina fellow Aaditya Shah, MD has published an excellent study titled, “Dark Adaptometry and Optical Coherence Tomography Angiography in Huntington Disease.” This pioneering research is among the first to indicate that retinal biomarkers may be present in patients with Huntington Disease (HD), offering a potentially transformative […] New Insights into Racial Disparities in Glaucoma: The Role of SDPR Gene Expression in Black Individuals May 21, 2024May 24, 2024 We are excited to share a new article by Ying-Bo Shui, Ying Liu, Andrew J. W. Huang & Carla J. Siegfried, titled “SDPR Expression in Human Trabecular Meshwork and Its Potential Role in Racial Disparities of Glaucoma,” has been published online in the journal Scientific Reports. This significant research highlights the molecular differences in gene […] Linking Cholesterol, NAD+ Depletion, and Age-Related Macular Degeneration April 17, 2024April 17, 2024 We are thrilled to announce the publication of a groundbreaking study titled “LXR/CD38 Activation Drives Cholesterol-Induced Macrophage Senescence and Neurodegeneration via NAD+ Depletion“, authored by Ryo Terao, MD, PhD; Mitsukuni Yoshida, MD, PhD; Rajendra Apte, MD, PhD; and colleagues from the Apte Lab. In this study, our researchers unveil critical molecular mechanisms linking dysregulated cholesterol […] Charles Pfeifer Wins the Prestigious 2024 Dr. Philip Needleman Pharmacology Award April 11, 2024April 11, 2024 We are thrilled to announce Charles Pfeifer as the distinguished recipient of the highly acclaimed 2024 Dr. Philip Needleman Pharmacology Award. This honor is bestowed upon a graduating student who has exhibited exceptional accomplishments in the field of Pharmacology. Founded in 1991 by Ms. Sima Needleman in tribute to her husband’s unwavering dedication to scholarship […] Understanding Retinal Detachment: Insights from Dr. Rajendra S. Apte’s Recent Study March 14, 2024March 29, 2024 We are thrilled to share with you a remarkable article titled “Retinal Detachment: Causes, Diagnosis, and Treatment Options” co-authored by Rajendra S. Apte, MD, PhD. This enlightening study, published in the renowned journal Nature, explores the intricate details of retinal detachment, providing valuable insights into its causes, diagnosis methods, and available treatment options. In this […] AMP Kinase Discovery in Photoreceptor Dysfunction by Tim Lee and Apte Lab January 17, 2024January 17, 2024 Graduate student Tim Lee from the Division of Biology and Biomedical Sciences (DBBS), working in collaboration with the Apte Lab, has published a new paper revealing a significant discovery in the realm of photoreceptor dysfunction. The research, titled “Identification of IMPDH as a Therapeutically Modifiable Target of AMP Kinase in Rod Photoreceptors,” sheds light on […] AMD Breakthrough: Uncovering Therapeutic Targets January 16, 2024January 16, 2024 Congratulations to MSTP Student Joseph Lin on Collaborative Breakthrough Publication in Cell Reports Medicine: Targeting cell-type-specific, choroid-peripheral immune signaling to treat age-related macular degeneration The Apte Lab is proud to announce the groundbreaking collaborative research publication by MSTP student Joseph Lin and the Ruzycki Lab. The study, published in Cell Reports Medicine, addresses age-related macular […] Innovative Research Unveils Potential Breakthrough in Diabetic Retinopathy Treatment October 31, 2023December 13, 2023 Diabetic retinopathy, a major concern for individuals with diabetes, has long been associated with the risk of vision loss and blindness. This condition, driven in part by the actions of retinal immune cells known as microglia, takes a significant toll on those it affects. In a groundbreaking publication, Charles Pfeifer, PhD, from the laboratory of […] Ocular Hypertension Treatment Study After 20 Years of Follow-up April 15, 2021April 16, 2021 Congratulations to Michael Kass, MD, Mae Gordon, PhD, and the Ocular Hypertension Study Group on their latest publication discussing their findings after 20 years of follow up! More than 20 years after the launch of a landmark clinical trial, follow-up examinations and analyses found that not all patients with elevated eye pressure need pressure-lowering treatment […] Apte lab and Genetic Department publication October 29, 2020November 4, 2020 “SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration” Congratulations to Dr. Rajendra Apte, his lab and the Genetics Department on their recent publication in eLife. Rajendra Apte, PhD and his lab with the help of Jeffrey Milbrandt, MD, PhD, Aaron DiAntonio, MD, PhD, Hiroki Kakita, MD, PhD and Yo Sasaki, PhD, from the […] Nerve injury appears to be root of diabetes-related vision loss June 1, 2017 Diabetes-related vision loss most often is blamed on blood vessel damage in and around the retina, but new research indicates that much of that vision loss may result from nerve cell injury that occurs long before any blood vessels are damaged. The finding — from scientists at Washington University School of Medicine in St. Louis — […] John F. Hardesty, MD, Department of Ophthalmology & Visual SciencesWashington University School of MedicineContact Us Facebook Instagram Twitter YouTube AFFILIATE INSTITUTIONS LINKS Faculty Job Openings Staff Job Openings Employee Portal (login required) Join our e-Newsletter mailing list ©2024 Washington University in St. Louis

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