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Skip to content AboutNews/In the MediaSiteman Cancer Center ranked No. 10 among U.S. cancer centersSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine has been named No. 10 among cancer centers nationally by U.S. News & World Report. The recognition is part of the overall ranking&＃8230;Read The Full Story Mission, Vision &＃038; History Why Siteman Diversity, Equity &＃038; Inclusion at SitemanAboutDiversity, Equity &＃038; Inclusion at SitemanLearn More Leadership Organizations Committees Partnerships Contact This is Cancer Learning With National Leaders In the News TreatmentClinicalHow Siteman is leading the way in personalized brain tumor treatmentIf you or a loved one have recently been diagnosed with a brain tumor, you likely feel a great deal of fear and have many questions. The brain is the epicenter of who we are,&＃8230;Read The Full Story Physician Directory Clinical Trials Search Patient Experience Siteman Psychology Service Survivorship Cardio-Oncology Lymphedema Surgery NCI Cancer Information A to Z Treatment Roles Cancer Types Bladder Brain Breast Cervical Childhood Cancers Colorectal Young Onset Colorectal Esophageal Gallbladder Head/Neck Kidney Leukemia Liver Lung Lymphoma Multiple Myeloma Myelodysplastic Syndromes (MDS) Ovarian Pancreatic Prostate Sarcoma/Rare Tumors Skin Stomach Testicular Thyroid Uterine The Siteman Approach Medical Therapy Expertise in Radiation Oncology Surgery Genetics and Hereditary Cancer Cancer Imaging Immunology and Immunotherapy Pathology Patient and Family Services Specialized Programs Stem Cell Transplant and Cellular Therapies Center Gynecologic Oncology Brain Tumor Center Sarcoma VisitingNews/In the MediaSiteman Cancer Center expands proton therapy treatmentSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is expanding proton therapy for patients by adding the latest, most innovative technology to its S. Lee Kling Proton Therapy Center with the addition of&＃8230;Read The Full Story Patient and Family Services Washington University Medical Campus West County St. Charles County South County Siteman Kids at St. Louis Children’s Hospital North County Illinois Siteman Cancer Network Cancer Care Clinic Barnard Health and Cancer Information Center Pharmacies Payment Information &＃038; Assistance Patient Rights Patient Privacy PreventionPreventionSiteman explains what every woman should know about endometrial cancer risk, symptoms and screeningEndometrial cancer is the fourth most common cancer for women in the United States. It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is&＃8230;Read The Full Story Your Disease Risk® Preventing Cancer Risk Factors Screening Smoking Cessation Mammography Genetic Counseling Cancer News in Context 8IGHTWAYS® to Prevent Cancer Health Disparities Community Outreach and Engagement ResearchResearchImmunity boosting treatment enhances CAR-T cell therapy for blood cancersAdvances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers. Six such CAR-T cell therapies are approved by the Food and Drug Administration&＃8230;Read The Full Story List of Researchers Significant Research Advances Learn About Clinical Trials Membership Information Plan to Enhance Diversity (PED) Research Programs Funding Opportunities Training &＃038; Education Shared Resources (Cores) Resources for Researchers SPORE in Pancreatic Cancer SPORE in Endometrial Cancer SPORE in Leukemia Center for Genome Integrity CliniciansNews/In the Media$5.3 million grant supports research into lung cancer recurrenceResearchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after&＃8230;Read The Full Story Physician Services Educational Programs GiveNews/In the MediaCouple honors physician with gift for distinguished professorshipEndowment will support leader in gynecologic oncology Financial adviser Elizabeth Mannen Berges lives each day with heightened gratitude for the basic components of a meaningful life—fulfilling work, caring relationships, and a sense of purpose. A&＃8230;Read The Full Story Siteman Advancement Office Volunteering and Contributing The Foundation for Barnes-Jewish Hospital AboutNews/In the MediaSiteman Cancer Center ranked No. 10 among U.S. cancer centersSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine has been named No. 10 among cancer centers nationally by U.S. News & World Report. The recognition is part of the overall ranking...Read The Full StoryAboutNews/In the MediaSiteman Cancer Center ranked No. 10 among U.S. cancer centersSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine has been named No. 10 among cancer centers nationally by U.S. News & World Report. The recognition is part of the overall ranking...Read The Full StoryMission, Vision & HistoryWhy SitemanDiversity, Equity &＃038; Inclusion at SitemanAboutDiversity, Equity &＃038; Inclusion at SitemanLearn MoreLeadershipOrganizationsCommitteesPartnershipsContactThis is CancerLearning With National LeadersIn the NewsTreatmentClinicalHow Siteman is leading the way in personalized brain tumor treatmentIf you or a loved one have recently been diagnosed with a brain tumor, you likely feel a great deal of fear and have many questions. The brain is the epicenter of who we are,...Read The Full StoryTreatmentClinicalHow Siteman is leading the way in personalized brain tumor treatmentIf you or a loved one have recently been diagnosed with a brain tumor, you likely feel a great deal of fear and have many questions. The brain is the epicenter of who we are,...Read The Full StoryPhysician DirectoryClinical Trials SearchPatient ExperienceSiteman Psychology ServiceSurvivorshipCardio-OncologyLymphedema SurgeryNCI Cancer Information A to ZTreatment RolesCancer TypesCancer TypesBladderBrainBreastCervicalChildhood CancersColorectalYoung Onset ColorectalEsophagealGallbladderHead/NeckKidneyLeukemiaLiverLungLymphomaMultiple MyelomaMyelodysplastic Syndromes (MDS)OvarianPancreaticProstateSarcoma/Rare TumorsSkinStomachTesticularThyroidUterineThe Siteman ApproachThe Siteman ApproachMedical TherapyExpertise in Radiation OncologySurgeryGenetics and Hereditary CancerCancer ImagingImmunology and ImmunotherapyPathologyPatient and Family ServicesSpecialized ProgramsSpecialized ProgramsStem Cell Transplant and Cellular Therapies CenterGynecologic OncologyBrain Tumor CenterSarcomaVisitingNews/In the MediaSiteman Cancer Center expands proton therapy treatmentSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is expanding proton therapy for patients by adding the latest, most innovative technology to its S. Lee Kling Proton Therapy Center with the addition of...Read The Full StoryVisitingNews/In the MediaSiteman Cancer Center expands proton therapy treatmentSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is expanding proton therapy for patients by adding the latest, most innovative technology to its S. Lee Kling Proton Therapy Center with the addition of...Read The Full StoryPatient and Family ServicesWashington University Medical CampusWest CountySt. Charles CountySouth CountySiteman Kids at St. Louis Children’s HospitalNorth CountyIllinoisSiteman Cancer NetworkCancer Care ClinicBarnard Health and Cancer Information CenterPharmaciesPayment Information &＃038; AssistancePatient RightsPatient PrivacyPreventionPreventionSiteman explains what every woman should know about endometrial cancer risk, symptoms and screeningEndometrial cancer is the fourth most common cancer for women in the United States. It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is...Read The Full StoryPreventionPreventionSiteman explains what every woman should know about endometrial cancer risk, symptoms and screeningEndometrial cancer is the fourth most common cancer for women in the United States. It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is...Read The Full StoryYour Disease Risk®Preventing CancerRisk FactorsScreeningSmoking CessationMammographyGenetic CounselingCancer News in Context8IGHTWAYS® to Prevent CancerHealth DisparitiesCommunity Outreach and EngagementResearchResearchImmunity boosting treatment enhances CAR-T cell therapy for blood cancersAdvances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers. Six such CAR-T cell therapies are approved by the Food and Drug Administration...Read The Full StoryResearchResearchImmunity boosting treatment enhances CAR-T cell therapy for blood cancersAdvances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers. Six such CAR-T cell therapies are approved by the Food and Drug Administration...Read The Full StoryList of ResearchersSignificant Research AdvancesLearn About Clinical TrialsMembership InformationPlan to Enhance Diversity (PED)Research ProgramsFunding OpportunitiesTraining &＃038; EducationShared Resources (Cores)Resources for ResearchersSPORE in Pancreatic CancerSPORE in Endometrial CancerSPORE in LeukemiaCenter for Genome IntegrityCliniciansNews/In the Media$5.3 million grant supports research into lung cancer recurrenceResearchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after...Read The Full StoryCliniciansNews/In the Media$5.3 million grant supports research into lung cancer recurrenceResearchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after...Read The Full StoryPhysician ServicesEducational ProgramsGiveNews/In the MediaCouple honors physician with gift for distinguished professorshipEndowment will support leader in gynecologic oncology Financial adviser Elizabeth Mannen Berges lives each day with heightened gratitude for the basic components of a meaningful life—fulfilling work, caring relationships, and a sense of purpose. A...Read The Full StoryGiveNews/In the MediaCouple honors physician with gift for distinguished professorshipEndowment will support leader in gynecologic oncology Financial adviser Elizabeth Mannen Berges lives each day with heightened gratitude for the basic components of a meaningful life—fulfilling work, caring relationships, and a sense of purpose. A...Read The Full StorySiteman Advancement OfficeVolunteering and ContributingThe Foundation for Barnes-Jewish Hospital Request an Appointment Request an Appointment For help choosing a doctor or making an appointment, please complete our form or call us directly. (800) 600-3606 I am a: Patient / New Patient Caregiver Physician Menu Skin Skin Our Approach to Skin Cancer Skin Cancer Specialist Team Skin Cancer Symptoms, Risk and Diagnosis Clinical Trials for Skin Cancer Basal Squamous Cell Skin Cancer Treatment Melanoma and Merkel Cell Cancer Treatment Eye Cancer Treatments Effects of Skin Cancer Treatment National Cancer Institute Information What's on this page Melanoma Basal cell skin cancer Squamous cell skin cancer Merkel cell Karposi sarcoma Mycosis Fungoides and the Sézary Syndrome (cutaneous lymphoma) | Treatment | Cancer Types | Skin | Our Approach to Skin Cancer Our Approach to Skin Cancer The skin is the body’s largest organ and has many functions: protection against heat, sunlight, injury, and infection; control of body temperature; and vitamin D production. The two main layers are the epidermis (upper or outer layer) and the dermis (lower or inner layer). The majority of skin cancers begin in the epidermis, which is made up of three kinds of cells: squamous cells, basal cells and melanocytes, the cells that make pigment and cause the skin to darken with ultraviolet light exposure. The most common skin cancers include: Melanoma Although less common than squamous cell or basal cell cancers, they are also more serious and are more likely to grow and spread if not diagnosed and treated early. Melanomas develop from melanocytes, the pigment-making cells of the skin. Melanocytes can also form non-cancerous moles. Melanoma can also affect the eye and eyelid. Basal cell skin cancer This is not only the most common type of skin cancer, but the most common type of cancer in humans. About 8 out of 10 skin cancers are basal cell carcinomas. They are usually found in skin exposed to sunlight. They rarely spread, but if left untreated, they can become locally destructive. Squamous cell skin cancer These cancers also appear on sun-exposed areas of the body such as the face, ears, neck, lips and backs of the hands. They can also develop in scars or chronic skin sores and can sometimes start within actinic keratosis, a pre-cancerous skin condition caused by too much exposure to the sun. Merkel cell Merkel cell carcinoma (MCC) is an uncommon type of skin cancer that can grow quickly and can be hard to treat if it spreads beyond the skin. Merkel cells are very close to nerve endings in the skin and are thought to be a type of neuroendocrine cell because they share some features with nerve cells and hormone-making cells. Karposi sarcoma This cancer develops from the cells that line lymph or blood vessels. Karposi sarcoma is caused by human herpes virus 8. It usually appears as tumors on the skin or on mucosal surfaces, such as inside the mouth, but tumors can also develop in other parts of the body. The most common type in the U.S. is AIDS-related Karposi syndrome. These cancers are treated as part of the HIV/AIDS management Mycosis Fungoides and the Sézary Syndrome (cutaneous lymphoma) This is a type on non-Hodgkin’s lymphoma in which malignant immune T-cells migrate to the skin causing lesions. Cutaneous lymphoma is often managed topically. Our dedicated skin cancer specialists see thousands of skin cancer patients a year. Some skin cancer patients require treatment from several medical and surgical specialists, including dermatologists, dermatologic surgeons, medical and surgical oncologists, radiologists, radiation oncologists, ophthalmologists, otolaryngologists and plastic surgeons. Washington University Physicians at Siteman from these fields routinely meet to coordinate and discuss treatment options for patients. In these multidisciplinary meetings, careful consideration is given to determining the best approach to treatment. Your care providers spend time with you, answering your questions and putting you in touch with resources. As a unique feature of your care, we also offer the services of a palliative care specialist who can help you fit treatment into your own special circumstances, if needed. At Siteman, once it has been determined that your skin condition may be cancerous, a biopsy is performed. During the biopsy all or part of the skin cancer is removed for examination under a microscope. From this skin sample a diagnosis will be made, and the appropriate method for removing the tumor will be determined. Washington University Physicians at Siteman are actively involved in clinical trials that investigate new chemotherapy regimens and other curative approaches. 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