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Mecham Distinguished Lectureship CBP/MCB Joint Retreat Open Search Faculty AllA B C D E F G H I J K L M N O P Q R S T U V W X Y Z Showing: All results Ghazaleh Ashrafi, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-273-1870 Email: [email protected] The Ashrafi lab uses genetic, biochemical, and quantitative optical imaging techniques to study metabolic regulation of neurotransmission. Kendall Blumer, PhD Professor of Cell Biology &＃038; Physiology Phone: 314-362-1668 Email: [email protected] The Blumer lab currently studies signal transduction mechanisms that cause uveal melanoma, a highly aggressive and deadly cancer, with the ultimate goal of discovering avenues leading to effective therapy for this currently untreatable cancer. Chun-Kan Chen, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-273-2787 Email: [email protected] The Chen lab utilizes multi-omic and high-throughput screening approaches to systematically investigate the regulation and function of circRNA in cells and develop novel circRNA technologies for translational applications. Clair Crewe, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-362-3240 Email: [email protected] The Crewe lab uses transgenic mouse lines, cell culture and biochemistry to understand extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation. Pan-Yue Deng, MD, PhD Associate Professor of Cell Biology &＃038; Physiology Phone: 314-362-5518 Email: [email protected] Lai Kuan Dionne, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-273-7929 Email: [email protected] Inter-organellar interactions between midbody, centrosome, and primary cilium in health and disease. Sergej Djuranovic, PhD Professor of Cell Biology &＃038; Physiology Phone: 314-362-9706 Email: [email protected] The Djuranovic Lab uses different biochemical, molecular biology and genetics techniques to investigate the process of gene expression regulation at the level of mRNA translation. Dennis Goldfarb, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-273-3991 Email: [email protected] The Goldfarb Lab is focused on computational mass spectrometry and proteomics with the goal of achieving comprehensive protein identification and quantification in complex biological samples. Subhadra Gunawardana, DVM, PhD Associate Professor of Cell Biology and Physiology Phone: 314-747-8501 Email: [email protected] Novel techniques for correcting type-1 diabetes without insulin, utilizing the beneficial effects of healthy adipose tissue: Subcutaneous transplantation of embryonic brown adipose tissue (BAT) has proven effective in reversing type 1 diabetes in mice, independent of insulin. Xue-Yan He, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-362-5296 Email: [email protected] The He Lab is dedicated to advancing knowledge of the mechanisms responsible for colorectal tumor progression, with a specific focus on Stress and its influence on the Tumor Microenvironment. James E. Huettner, PhD Professor of Cell Biology &＃038; Physiology Phone: 314-362-6628 Email: [email protected] The Huettner lab uses electrophysiology to study native and recombinant mammalian glutamate receptors, in order to elucidate their interactions with components of the lipid bilayer, and their pharmacology and role in synaptic transmission. Silvia Jansen, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-273-1852 Email: [email protected] The Jansen Lab is focused on elucidating the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions ranging from cell migration and cytokinesis to neurogenesis. David J. Kast, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-273-1853 Email: [email protected] The Kast Lab studies the biogenesis and dynamics of intracellular membrane compartments; molecular mechanisms and regulation of cytoskeleton and membrane interactions. Vitaly A. Klyachko, PhD Professor of Cell Biology &＃038; Physiology Phone: 314-362-5517 Email: [email protected] The Klyachko Lab studies the mechanisms governing synaptic transmission are critical to our understanding of how information is transmitted in the brain, yet they remain among the most fundamental unresolved questions in neurobiology. Sun Joo Lee, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-362-6629 Email: [email protected] Molecular basis of ion channel function, and in particular on membrane lipid-channel interactions. Polina Lishko, PhD Professor of Cell Biology &＃038; PhysiologyBJC Investigator Phone: 314-362-3566 Email: [email protected] The Lishko Lab focuses on molecular mechanisms of bioactive lipid signaling, investigating bioelectricity and regulation of ion channels, physiology of the retina, fluid flow in the brain, fertility, reproductive biology research, neurodegeneration and vision. M. Benjamin Major, PhD Alan A. and Edith L. Wolff ProfessorDepartment of Cell Biology &＃038; PhysiologyDepartment of Otolaryngology Phone: 314-273-3675 Email: [email protected] The Major Lab uses mass spectrometry-based proteomics and chemical and genetic screens to study signal transduction in human disease, with a particular focus on understudied kinases and the WNT and the KEAP1/NRF2 pathways. Grigory I. Maksaev, PhD Instructor in Cell Biology &＃038; Physiology Phone: 314-747-5444 Email: [email protected] Structure, function and regulation of mechanosensitive ion channels. Dario Maschi, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-362-6630 Email: [email protected] Developing new approaches for studying synaptic function using super-resolution live imaging microscopy and advanced computational imaging analysis Jongyun Myeong, PhD Instructor in Cell Biology &＃038; Physiology Phone: 314-362-5518 Email: [email protected] Colin G. Nichols, PhD Carl Cori Professor, Department of Cell Biology &＃038; PhysiologyDirector, Center for the Investigation of Membrane Excitability Diseases Phone: 314-362-7463 Email: [email protected] The Nichols Lab&＃8217;s research spans from the molecular basis of potassium channel activity to human disease. His work on KATP channel activity led to the discovery of the mechanism of human neonatal diabetes and a revolution in therapy – affected children can now take once a day pills – even dissolved in milk – rather than traumatic, three times a day insulin injections. David J. Pagliarini, PhD Hugo F. &＃038; Ina C. Urbauer Professor and BJC InvestigatorDepartments of Cell Biology &＃038; Physiology, Biochemistry and Molecular Biophysics, and Genetics Phone: 314-273-2331 Email: [email protected] The Pagliarini Lab is an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Slavica Pavlovic-Djuranovic, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-362-6675 Email: [email protected] David W. Piston, PhD Edward J. Mallinckrodt, Jr. Professor and Head of Cell Biology &＃038; Physiology Phone: 314-362-9121 Email: [email protected] The Piston Lab studies the molecular pathways of islet hormone secretion. Paul H. Schlesinger, MD, PhD Associate Professor of Cell Biology &＃038; Physiology Phone: 314-362-2223 Email: [email protected] Study several areas that focus on cell membrane function, including activation, and in-membrane dynamics of BCl-2 family proteins, the critical arbiters of cell death in humans, pore forming antimicrobial peptides, membrane repair, perflurocarbon nano-delivery systems, malaria parasite host/cell interactions. Sheila A. Stewart, PhD Gerty Cori Professor and Vice Chair, Department of Cell Biology &＃038; PhysiologyProfessor, Department of Medicine Phone: 314-304-2157 Email: [email protected] The Stewart lab&＃8217;s research focuses on understanding how age-related changes in noncancerous cells (referred to as stroma) participate in cancer development. Amber Stratman, PhD Assistant Professor of Cell Biology &＃038; Physiology Phone: 314-273-7928 Email: [email protected] The Stratman Lab studies the mechanisms regulating blood vessel formation, stabilization, and blood flow sensing during development and disease. Heather L. True, PhD David English Smith Professor, Department of Cell Biology &＃038; Physiology Phone: 314-362-3934 Email: [email protected] The True Lab studies protein misfolding and aggregation are the hallmark of several neurodegenerative diseases and other disorders. Nathaniel York, PhD Instructor in Cell Biology &＃038; Physiology Phone: 314-362-6629 Email: [email protected] Impact of gain- and loss-of-function in KATP on smooth muscle cell electrophysiology. Zhongsheng You, PhD Professor of Cell Biology &＃038; Physiology Phone: 314-362-9893 Email: [email protected] The You Lab studies the DNA damage response and replication stress response in human cells that are essential for genome maintenance and cancer avoidance. Emily W. Zarbock, PhD Instructor in Cell Biology &＃038; Physiology Phone: 314-273-3991 Email: [email protected] Mass Spectrometry, Proteomics People Faculty Current Trainees Postdoctoral Researchers Research Staff Administrative Emeritus Faculty Alumni Department of Cell Biology & PhysiologyWashington University School of Medicine660 S. Euclid Ave.MSC-8228-03-04St. Louis, MO 63110314-273-8536 Instagram ©2024 Washington University in St. Louis