新利18体|新利18澳门

Skip to content Skip to search Skip to footer Department of Obstetrics & Gynecology Open Menu Back Close Menu Search for: Search Close Search AboutAbout Vision, Mission, Values &＃038; CARE Model Department DirectoryDepartment Directory Assistants &＃038; Administrative Staff Diversity, Equity &＃038; Inclusion Locations &＃038; Facilities COVID-19 Response History of the Department Open Faculty Positions Links for Employees Quick Links DivisionsDivisions Center for Reproductive Health Sciences (CRepHS) Division of Clinical Research (DCR) Division of Complex Family Planning, Contraception, & Gynecology Division of Urogynecology & Reconstructive Pelvic Surgery Division of Academic Specialists of Obstetrics &＃038; Gynecology Division of Gynecologic Oncology Division of Maternal-Fetal Medicine &＃038; Ultrasound Division of Minimally Invasive Gynecologic Surgery Division of Pediatric and Adolescent Gynecology Division of Reproductive Endocrinology &＃038; Infertility Patient CarePatient Care MyChart Patient Portal COVID-19 Guidelines for Patients Referring a Patient Clinical Trials Obstetrics: Pregnancy &＃038; Childbirth High-Risk Pregnancy Ultrasound &＃038; Genetic Counseling Fertility &＃038; Reproductive Medicine Complex Family Planning, Contraception, &＃038; Gynecology Gynecology Gynecologic Cancer Gynecologic Surgery Pelvic Floor, Bladder &＃038; Urogynecology Pediatric &＃038; Adolescent Gynecology Share Your Feedback Education &＃038; TrainingEducation &＃038; Training Grand Rounds Residency Fellowships Training Sites About St. Louis Medical Students Visiting Residents and Fellows Research Seminars Postdoctoral Fellowship in Women’s Health with a focus on Female Lower Urinary Tract Disorders (T32) Professional Development Series (PDS) ResearchResearch Division of Clinical Research (DCR) Center for Reproductive Health Sciences (CRepHS) Research Strengths Clinical Trials Route 66 Endometrial Cancer SPORE Recent Publications Training Opportunities Investigator Resources, Core Facilities &＃038; Funding Opportunities NewsNews Newsletters Annual Report EventsEvents Calendar View Alumni &＃038; Giving Open Search Route 66 Endometrial Cancer SPORE David Mutch, MD WashU OBGYN Kimberly Leslie, MD University of New Mexico Doris Benbrook, PhD University of Oklahoma The Route 66 Endometrial Cancer SPORE brings together interactive research teams from three institutions to create a dynamic translational research program aimed at developing and testing new strategies to prevent and treat endometrial cancer. This SPORE includes three research projects; an administrative core; a biostatistics and bioinformatics core; a biospecimens, metabolomics, and pathology core; and developmental research and career enhancement programs. The three projects, chosen and refined with extensive input from our internal and external advisory boards, are designed to have significant potential to change clinical practice within five years: Project 1: HSPA Proteins in Advanced and Recurrent Endometrial Cancer Therapy Project 2: Inhibiting AXL to Improve Treatment Response in Endometrial Cancer Project 3: Improving Primary Prevention and Uterine Preservation in Premenopausal Women with Obesity and Endometrial Hyperplasia All three projects include clinical trials and represent carefully chosen marriages between selected endometrial cancer research priorities and the strengths of Washington University in St. Louis and our collaborators at the University of New Mexico and the University of Oklahoma Health Sciences Center. The overall aims are to: Test promising new therapies to treat or prevent endometrial cancer; Elucidate the key biologic processes that drive endometrial cancer and develop novel biomarkers to predict development of endometrial cancer and response to therapies; Leverage and enhance capacities of shared research resources; Recruit and mentor new investigators and support innovative ideas in translational endometrial cancer research; Facilitate collaboration of those interested in endometrial cancer research; and Ensure equitable enrollment in clinical trials and involvement of diverse community members and investigators in research. In completing the work proposed, we will test new strategies to prevent or treat endometrial cancer. Future work can be directed at moving the most promising treatment approaches into larger trials. Additionally, we will obtain an unprecedented level of molecular, cellular, immunologic, and metabolomic detail regarding endometrial cancer and response to treatment, which will likely lead to development of additional novel clinical trials. Finally, by developing new ideas, investigators, and collaborations, we will expand the breadth and depth of research aimed at treating or preventing endometrial cancer. Research Research Strengths Training Opportunities Investigator Resources, Core Facilities &＃038; Funding Opportunities Route 66 Endometrial Cancer SPORE Project 1: Targeting HSPA Proteins in Advanced and Recurrent Endometrial Cancer Therapy Project 2: Inhibiting AXL to Improve Treatment Response in Endometrial Cancer Project 3: Primary Prevention and Uterine Preservation in Premenopausal Women with Obesity and Endometrial Hyperplasia/Cancer Administrative Core Core 1: Biostatistics and Bioinformatics Core Core 2: Biospecimen, Metabolomics, and Pathology Core Career Enhancement &＃038; Developmental Research Programs Recent Publications Department of Obstetrics & GynecologyWashington University School of MedicinePost Address: MSC 8064-37-1005, 660 S. Euclid Ave.St. Louis, MO 63110Patients: 314-362-7135Links for Employees Instagram Twitter Affiliate institutions ©2024 Washington University in St. Louis