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At Washington University School of Medicine, the BJC Investigators Program is assembling a cohort of some of the most innovative and accomplished basic life scientists in their fields. Launched in 2017, the program will eventually bring 10 renowned investigators to the medical school and the life sciences ecosystem of St. Louis. The BJC Investigator Program is a joint effort between BJC HealthCare and Washington University. Embedding in the rich network of mentors and collaborators at Washington University, this cohort of investigators is supercharging the school&＃8217;s ever-expanding capacity to advance medical care today and prepare the leaders of tomorrow. Meet the investigators Each BJC Investigator brings a wealth of talent, creativity and expertise that have led to foundational discoveries in biology. They have pioneered innovative approaches to major biological quandaries, and their work is expected to accelerate progress toward finding treatments and cures for diseases ranging from psychiatric disorders to viral infections to birth defects. Adam Kepecs, PhD Robert J. Terry Professor of Neuroscience Professor of Psychiatry As part of his investigations into the neurobiology of behavior, Adam Kepecs, PhD, has helped describe the neural circuitry that underlies decision-making. His lab is focused on understanding the computational processes of cognition and applying that knowledge to treating mental illness. He has been a Kavli Frontiers of Science fellow, a John Merck Scholar, a Klingenstein Fellow, an Alfred P. Sloan research fellow, and the recipient of a McKnight Foundation Memory and Cognitive Disorders Award. Read the announcement » Jonathan Kipnis, PhD Alan A. and Edith L. Wolff Distinguished Professor of Pathology and Immunology Jonathan Kipnis, PhD, is well known for his research into the immune system’s influence on neurological function, including his stunning discovery of lymphatics, the immune system’s drainage ducts, around the mammalian brain. He has received the Prize of Excellence from the Israeli Knesset, the Jordi Folch-Pi Award from the American Society for Neurochemistry and the NIH Director’s Pioneer Award. Read the announcement » Polina V. Lishko, PhD Professor of Cell Biology & Physiology Polina V. Lishko, PhD, is a noted molecular biologist and entrepreneur whose work has advanced understanding in fields as varied as reproductive biology, vision and neurodegeneration. She is best known for basic reproductive biology research that could lead to alternatives to hormonal contraceptives. She is also investigating a potential link between menopause and increased Alzheimer&＃8217;s risk, and developing an eyedrop to prevent age-related macular degeneration. Among her numerous accolades, Lishko was selected as a Sloan Foundation Fellow and a Pew Scholar in the Biomedical Sciences in 2015, and she received a MacArthur &＃8220;Genius Grant&＃8221; in 2020. Read the announcement » Carolina López, PhD Professor of Molecular Microbiology Carolina López, PhD, studies the interactions between viruses and the hosts they infect. Her lab has provided foundational insights into the ability of non-standard viral genomes—versions of a virus’s genome that aren’t the full-length copy—to affect the course of infection. She is a fellow of the NIH-funded Professional Mentoring Skills Enhancing Diversity (PROMISED) Program, a recipient of a faculty mentoring award from the University of Pennsylvania, where she was an associate professor of pathobiology, and a U.S. Fulbright Scholar. Read the announcement » Helen McNeill, PhD Larry J. Shapiro and Carol-Ann Uetake-Shapiro Professor of Developmental Biology Helen McNeill, PhD, joined Washington University School of Medicine in 2018 as the inaugural BJC Investigator. Her research focuses on the processes that govern early embryonic development, in particular, molecules called giant cadherins that bind cells together during tissue growth. This work has implicated giant cadherins in numerous conditions, including spina bifida and congenital kidney diseases. Her accomplishments have been recognized by the Petro-Canada Young Innovator Award, the Lloyd S.D. Fogler, QC, Award of Excellence and a Canada Tier 1 Research Chair. Read the announcement » Dave Pagliarini, PhD Hugo F. and Ina C. Urbauer Professor of Cell Biology and Physiology Dave Pagliarini, PhD, studies mitochondria—the energy-producing organelles within cells—and has made major advances in identifying their components and their roles in health and disease. His work has earned him the Glenn Award for Research in Biological Mechanisms of Aging, the Searle Scholar Award, the Protein Science Young Investigator Award from The Protein Society, the Earl and Theresa Stadtman Young Scholar Award from the American Society for Biochemistry and Molecular Biology and the Presidential Early Career Award for Scientists and Engineers from the National Science Foundation. Read the announcement » Kodi S. Ravichandran, PhD Director of the Division of Immunobiology, Department of Pathology and Immunology Robert L. Kroc Professor of Pathology and Immunology A world leader in understanding innate immunity, Kodi S. Ravichandran, PhD, and his team have identified key mechanisms by which dead cells are cleared from the body in a process called efferocytosis. Failures in this process are linked to a host of autoinflammatory diseases. Ravichandran has received many honors and awards, including State of Virginia Outstanding Scientist of the Year and the University of Virginia Distinguished Scientist Award, among others. He has been dedicated to teaching and mentoring dozens of postdoctoral fellows and graduate students, many of whom have gone on to success in academia and industry. Read the announcement » Latest news from BJC Investigators Neurons help flush waste out of brain during sleep Adeoye, Guilak, Gutmann, Kipnis elected to National Academy of Medicine Lishko named BJC Investigator More BJC Investigator Program stories » Selection committee and advisory board A search committee of about 50 researchers at Washington University School of Medicine selects BJC Investigators based on their track record of pathbreaking science, transformative thinking, and creating research hubs that catalyze further work. A seven-member external advisory board also assists in BJC Investigator recruitment. Representing top research institutions across the country, advisory board members include National Academy of Sciences and National Academy of Medicine members, Howard Hughes Medical Institute investigators, a member of the Royal Swedish Academy of Sciences, and a recipient of the Nobel Prize in Chemistry. BJC Investigator External Advisory Board members: Helen M. Blau, PhD Stanford University Brian J. Druker, MD Oregon Health & Science University Knight Cancer Institute Brian Kobilka, MD Stanford University School of Medicine Ruth Lehmann, PhD Massachusetts Institute of Technology Dan R. Littman, MD, PhD New York University School of Medicine Joshua R. Sanes, PhD Harvard University Joan A. Steitz, PhD Yale University Directories Maps &＃038; Directions Calendars Contact Giving Follow us on Facebook Follow us on Twitter Follow us on Instagram Subscribe to us on YouTube Follow us on LinkedIn Follow us on TikTok Washington University School of Medicine 660 S. 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