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Skip to main navigation Skip to search Skip to main content Research Profiles at Washington University School of Medicine Home Help & FAQ Home Profiles Departments, Divisions and Centers Research output Search by expertise, name or affiliation View Scopus Profile Christina Stallings Professor of Molecular Microbiology Department of Molecular MicrobiologyRoy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)DBBS - Biochemistry, Biophysics, and Structural BiologyDBBS - ImmunologyDBBS - Molecular Microbiology and Microbial PathogenesisDBBS - Plant and Microbial BiosciencesInstitute for Public HealthInstitute of Clinical and Translational Sciences (ICTS)Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)  https://orcid.org/0000-0002-2747-5618 Willing to MentorAvailable to Mentor:PhD/MSTP Students 4591 Citations 20052024 Research activity per year Overview Fingerprint Network Research output (69) Similar Profiles (10) Personal profile Research interestsOur laboratory focuses on the adaptation of Mycobacteria to host-inflicted stresses and persistent infection. At least 30% of the world’s population is infected with latent Mycobacterium tuberculosis, which in some individuals will reactivate and cause an estimated 1.8 million deaths a year. This health crisis is exacerbated by the alarming emergence of multi-drug and extensively drug resistant strains. The inadequacies of present Tuberculosis therapies demand the discovery of new agents to treat M. tuberculosis infection, which requires insight into the pathways involved in M. tuberculosis pathogenesis. The general approach of our laboratory is to integrate in vivo disease modeling, molecular biology, and biochemistry to provide answers to the fundamental biological questions regarding molecular pathogenesis and yield therapeutic strategies for treatment of mycobacterial infections. Lab Website Available to Mentor:PhD/MSTP Students Fingerprint Dive into the research topics where Christina Stallings is active. These topic labels come from the works of this person. Together they form a unique fingerprint. 10 Similar Profiles Mycobacterium tuberculosis Medicine & Life Sciences 100% Tuberculosis Medicine & Life Sciences 50% DNA-Directed RNA Polymerases Medicine & Life Sciences 40% Autophagy Medicine & Life Sciences 36% Mycobacterium Medicine & Life Sciences 32% Infections Medicine & Life Sciences 19% Human Herpesvirus 3 Medicine & Life Sciences 17% Isoniazid Medicine & Life Sciences 16% View full fingerprint Collaborations and top research areas from the last five years Recent external collaboration on country/territory level. Dive into details by clicking on the dots or Select a country/territory from the list Dive into details Select a country/territory to view shared publications and projects Close Select a country/territory from the list Explore network further Research output Research output per year 2005 2016 2017 2018 2019 2021 2023 2024 52 Article 8 Review article 3 Comment/debate 3 Short survey 3 More 1 Chapter 1 Editorial 1 Letter Research output per year Research output per year Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis infection in miceFeng, S., McNehlan, M. E., Kinsella, R. L., Sur Chowdhury, C., Chavez, S. M., Naik, S. K., McKee, S. R., Van Winkle, J. A., Dubey, N., Samuels, A., Swain, A., Cui, X., Hendrix, S. V., Woodson, R., Kreamalmeyer, D., Smirnov, A., Artyomov, M. N., Virgin, H. W., Wang, Y. T. & Stallings, C. L., Mar 2024, In: Nature microbiology. 9, 3, p. 684-697 14 p.Research output: Contribution to journal › Article › peer-review Autophagy 100% Tuberculosis 85% T-Lymphocytes 64% Macrophages 52% Mycobacterium tuberculosis 43% 1 Scopus citations BHLHE40 Regulates Myeloid Cell Polarization through IL-10–Dependent and –Independent MechanismsHendrix, S. V., Mreyoud, Y., McNehlan, M. E., Smirnov, A., Chavez, S. M., Hie, B., Chamberland, M. M., Bradstreet, T. R., Webber, A. M., Kreamalmeyer, D., Taneja, R., Bryson, B. D., Edelson, B. T. & Stallings, C. L., Jun 1 2024, In: Journal of Immunology. 212, 11, p. 1766-1781 16 p.Research output: Contribution to journal › Article › peer-review Myeloid Cells 100% Tuberculosis 80% Interleukin-10 58% Macrophages 34% Granulocyte-Macrophage Colony-Stimulating Factor 34% Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosisHarrison, G. A., Wang, E. R., Cho, K., Mreyoud, Y., Sarkar, S., Almqvist, F., Patti, G. J. & Stallings, C. L., Mar 2024, In: mBio. 15, 3Research output: Contribution to journal › Article › peer-review Open Access Multidrug-Resistant Tuberculosis 100% Isoniazid 93% Mycobacterium tuberculosis 80% isonicotinyl-NAD 77% Energy Metabolism 16% Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophagesKinsella, R. L., Kimmey, J. M., Smirnov, A., Woodson, R., Gaggioli, M. R., Chavez, S. M., Kreamalmeyer, D. & Stallings, C. L., Jun 2023, In: PLoS biology. 21, 6, e3002159.Research output: Contribution to journal › Article › peer-review Open Access Mycobacterium tuberculosis 100% autophagy 99% Neutrophil Infiltration 95% Autophagy 80% neutrophils 78% 4 Scopus citations Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancyPopli, P., Tang, S., Chadchan, S. B., Talwar, C., Rucker, E. B., Guan, X., Monsivais, D., Lydon, J. P., Stallings, C. L., Moley, K. H. & Kommagani, R., May 22 2023, In: Developmental cell. 58, 10, p. 885-897.e4Research output: Contribution to journal › Article › peer-review Open Access Beclin-1 100% Developmental 95% Autophagy 75% Stem Cells 57% Apoptosis 47% 4 Scopus citations View all 69 Research outputs Powered by Pure, Scopus & Elsevier Fingerprint Engine™ All content on this site: Copyright © 2024 Elsevier B.V. or its licensors and contributors. 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