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Skip to content Skip to search Skip to footer Ophthalmology & Visual Sciences Open Menu Back Close Menu Search for: Search Close Search Home About UsAbout Us Latest News and Announcements Faculty Directory History Becker Collection EducationEducation Residency ProgramResidency Program Meet the Residents What Distinguishes Us? Application Process Research OpportunitiesResearch Opportunities Ongoing and Completed Research Resident Call Schedule Subspecialty Rotations Living In St. Louis Frequently Asked Questions Clinical FellowshipsClinical Fellowships Meet the Fellows Corneal, External Disease, and Refractive Fellowship Glaucoma Fellowship Ocular Immunology/Uveitis Fellowship Ophthalmic Plastic &＃038; Reconstructive Surgery Fellowship Neuro-Ophthalmology Fellowship Pediatric Ophthalmology and Strabismus Fellowship Vitreoretinal Disease and Surgery Fellowship Optometry Residency Program ResearchResearch DOVS Labs ITVS Pathway T32 Vision Science Training Grant Vision Core GrantVision Core Grant Molecular Genetics Service Core Morphology &＃038; Imaging Core Vision Function Testing Core Graduate Course BIO5501 Student Research Opportunities LASIK Surgery Center Patient CarePatient Care Clinical Specialties Clinical Offices Clinical Trials Prepare for your visit Giving Contact UsContact Us Department Contacts AlumniAlumni Alumni Roster Alumni Videos PhotosPhotos Alumni Photos June 2012 Graduation Welcome Reception 2015 Hardesty Chair 5-31-12 Alumni Newsletters Association Dues EventsEvents Named Lectureship Series DOVS Grand Rounds Archives Open Search DOVS News Education Fellows in the news Research Publications Exploring Retinal Biomarkers in Huntington Disease: A Groundbreaking Study By Brianna • May 24, 2024May 29, 2024 In a significant leap forward for neurodegenerative disease research, Retina fellow Aaditya Shah, MD has published an excellent study titled, &＃8220;Dark Adaptometry and Optical Coherence Tomography Angiography in Huntington Disease.&＃8221; This pioneering research is among the first to indicate that retinal biomarkers may be present in patients with Huntington Disease (HD), offering a potentially transformative approach to monitoring this debilitating condition. Aaditya Shah, MDDepartment of Ophthalmology and Visual Sciences Retina Fellow 2023-2025 Huntington Disease, a genetic disorder that causes the progressive breakdown of nerve cells in the brain, has long posed challenges in both diagnosis and management. Traditional methods rely heavily on neurological assessments and genetic testing. However, Shah&＃8217;s study suggests a novel, non-invasive technique that could revolutionize patient care. By utilizing Dark Adaptometry and Optical Coherence Tomography Angiography (OCTA), Shah&＃8217;s research explores the potential of the retina as a window to brain health. Dark adaptometry measures the eye&＃8217;s ability to adjust to darkness, while OCTA provides detailed images of the retina&＃8217;s blood vessels. These techniques combined may reveal changes in the retinal structure and function that correlate with the progression of Huntington Disease. The implications of Shah&＃8217;s findings are profound. If retinal biomarkers can be reliably identified and monitored, healthcare providers might have a new tool to track disease progression and evaluate the effectiveness of treatments without the need for invasive procedures. This advancement could lead to earlier interventions and more personalized care plans for those living with Huntington Disease. While this study marks an exciting breakthrough, it also underscores the need for further research. Continued exploration and validation of these findings are crucial to transitioning from experimental results to practical clinical applications. Shah&＃8217;s work opens the door to a new realm of possibilities, setting the stage for future innovations in the management of Huntington Disease. In conclusion, Aaditya Shah&＃8217;s study represents a significant stride in the fight against neurodegenerative diseases. By highlighting the potential of retinal biomarkers, this research not only broadens our understanding of Huntington Disease but also paves the way for more effective, non-invasive patient monitoring. The journey is far from over, but the path ahead looks promising. Read the publication John F. Hardesty, MD, Department of Ophthalmology & Visual SciencesWashington University School of MedicineContact Us Facebook Instagram Twitter YouTube AFFILIATE INSTITUTIONS LINKS Faculty Job Openings Staff Job Openings Employee Portal (login required) Join our e-Newsletter mailing list ©2024 Washington University in St. Louis