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Skip to content THE SOURCE Close TopicsTopics Arts & Culture Business & Entrepreneurship Campus & Community Humanities & Society Medicine & Health Science & Technology SchoolsSchools Arts & Sciences Brown School McKelvey School of Engineering Olin Business School Sam Fox School of Design & Visual Arts School of Continuing & Professional Studies School of Law School of Medicine PublicationsPublications Newsroom The Record Washington Magazine Search Menu Search for: Search Close THE RECORD Sections Announcements Notables Obituaries Research Wire The View From Here Washington People Biologists take closer look at stress response in cells June 18, 2024 SHARE Zaher When cells encounter challenges like nutrient shortages, they activate a response known as the integrated stress response, which produces specific proteins to help the cells survive. A study led by Hani Zaher, a professor of biology in Arts & Sciences at Washington University in St. Louis, dives into the mechanisms behind this response. The scientists investigated what happens to protein production when a translation initiation factor called elF4E is removed in yeast cells. They found that the absence of eIF4E led to an increase in the production of Gcn4, one of the key proteins associated with integrated stress response. The researchers also shared a new model to explain their observations, linking some activity to changes in the speed at which ribosomes move along genetic instructions. Findings from this study, published in June in Molecular Cell, may have implications for why certain cancers alter the concentrations of translation factors. Read more on the biology website. SHARE SectionsResearch Wire TopicsBiologyScience & Technology Schools Arts & SciencesRead more stories from Arts & SciencesVisit Arts & Sciences Leave a Comment Comments and respectful dialogue are encouraged, but content will be moderated. Please, no personal attacks, obscenity or profanity, selling of commercial products, or endorsements of political candidates or positions. We reserve the right to remove any inappropriate comments. We also cannot address individual medical concerns or provide medical advice in this forum. You Might Also Like Seeking to avoid ‘full lockdown,’ cells monitor ribosome collisions December 17, 2020 Published In Newsroom Stories Scientists find way to supercharge protein production December 18, 2019 Published In Newsroom Stories Unlocking the &＃8216;chain of worms&＃8217; April 15, 2024 Published In Newsroom Stories Latest from the Record Announcements Parking shares latest update Staff leadership program applications due May 31 Peace Park planting May 18 Notables Bose named Fulbright Scholar Oppenheimer named Religion & Politics executive editor Lucey receives sleep science award  Obituaries Stan H. Braude, professor of practice in Arts &＃038; Sciences, 62 Liz Colletta, longtime accounting employee, 55 Eduardo Slatopolsky, professor emeritus of medicine, 89 Research Wire Altered carbon points toward sustainable manufacturing Advancing robot autonomy in unpredictable environments Sampling eDNA for global biodiversity census The View From Here 06.19.24 05.31.24 05.15.24 Washington People Sadie Williams Clayton Caitlyn Collins Kim Thuy Seelinger Who Knew WashU? Who Knew WashU? 1.27.21 Who Knew WashU? 1.13.21 Who Knew WashU? 12.9.20 Publications Washington Magazine Newsroom Record Explore Bookshelf Video Gallery Connect Media Resources Contact Facebook Instagram ©2024 Washington University in St. Louis Go back to top