18新利官方|新利18存款

Find a Doctor Admissions Giving Information for   Announcements   WUSTL Directories Announcements Updates on campus events, policies, construction and more. Dean&＃8217;s 2023 State of the School address available online Notice of data security incident COVID-19: Medical Campus updates close   Information for Our Community Whether you are part of our community or are interested in joining us, we welcome you to Washington University School of Medicine. Prospective Students Current Students Faculty Staff Alumni & Friends Administrators Researchers Job Seekers close   Search Home About Education Research Patient Care News Home About Welcome from the Dean Mission &＃038; Vision Diversity, Equity &＃038; Inclusion Diversity &＃038; Inclusion Commitment Facts Leadership About Dean Perlmutter The Medical Campus Campus Construction &＃038; Growth Facilities &＃038; Services Faculty Recognition History About St. Louis Education Areas of Study Financial Support Traditions MD White Coat Ceremony Match Day Commencement Research Training Programs Tradition of Innovation BJC Investigators Nobel Prize Winners Patient Care Hospital Partners Patient Stories Clinical Trials News Media Contacts Show Me the Science Podcast Announcements Prospective Students Current Students Faculty Staff Alumni & Friends Administrators Researchers Job Seekers Directories A to Z Index Departments & Programs Administrative Offices &＃038; Services Maps & Directions Street &＃038; Pedestrian Closures Calendar Contact Giving Policies Links to Third-Party Websites Website Privacy Policy Visit the News Hub News ReleaseRacial equity in Alzheimer’s research focus of $7 million in grantsFunds to support diverse volunteer registry, study of social risk factors affecting Black peopleby Tamara Bhandari•December 14, 2021Getty ImagesTwo research teams at Washington University in St. Louis — one led by Joyce Balls-Berry, PhD; the other led by Darrell Hudson, PhD, and Ganesh Babulal, PhD, OTD — have received grants totaling $7 million to advance racial equity in Alzheimer&＃039;s disease research. The burden of Alzheimer’s disease doesn’t fall on all communities equally. Black Americans face about double the risk of developing the devastating neurodegenerative disease than non-Hispanic white Americans do. The factors that place Black people at elevated risk remain poorly understood, partly because Black people historically and systematically have been underrepresented in Alzheimer’s studies. Without a sufficiently large pool of Black study participants, it is not possible to investigate thoroughly the myriad social and other factors that put Black people at risk. Two new grants awarded to researchers at Washington University in St. Louis will support efforts to bring more Black Americans into Alzheimer’s research studies to better understand the health challenges facing the community. Joyce Balls-Berry, PhD, an associate professor of neurology at the School of Medicine, has received a $3.4 million grant to recruit Black Americans and other members of under-resourced communities into a registry for research studies. Darrell Hudson, PhD, an associate professor of public health at the Brown School, and Ganesh M. Babulal, PhD, OTD, an assistant professor of neurology at the School of Medicine, have jointly received a $3.7 million grant to investigate risk factors for cognitive decline among Black Americans. Both studies are supported by the National Institute on Aging of the National Institutes of Health (NIH). Building a diverse registry that benefits participants and researchers Balls-Berry Balls-Berry’s work builds on the groundwork laid by the African American Advisory Board at Washington University’s Charles F. and Joanne Knight Alzheimer Disease Research Center. Established in 2000 by national civil rights activist Norman Seay and John C. Morris, MD, the Harvey A. and Dorismae Hacker Friedman Distinguished Professor of Neurology, the advisory board has steadily expanded African American participation in Alzheimer’s studies at Washington University by promoting culturally sensitive and appropriate outreach strategies. But much work remains to be done, Balls-Berry said. The number of Black volunteers is still relatively small, and she worries about overburdening them with too many requests for study participation. Consequently, she is launching the COEQUAL Registry (Creating Opportunities to Increase Health Equity and Equality for Persons at risk of Alzheimer Disease and Related Dementias). The plan is to use a patient- and community-engaged framework to recruit, enroll and retain 2,000 new volunteers. Historically, members of under-represented groups too often have been left out of the design and planning process for biomedical studies, resulting in research that does not meet their needs, Balls-Berry said. To ensure that the registry will benefit participants and their communities as well as researchers, she is working closely with civic leaders and patient and family advocates to determine every aspect of the registry: which data to collect, how to collect and utilize them, how to give participants and the community access to data in the registry, and how to report to the community findings from studies based on the data. “As a Black woman scientist, I always think about the fact that many times our voices aren’t heard,” Balls-Berry said. “I used to teach ‘Intro to Community-Engaged Research,’ and I would tell my students, ‘You drop down into the community. You ask a ton of questions. You draw some blood. You give out a few gift cards as a thank you. You write some papers. You get promoted. But you never come back to present your findings. You&＃8217;ve never asked the question, ‘How can this data be used by the local community to inform policy changes in those areas?’ That’s how we don’t want to do it. We want to consider the issues around the cultural impact of the science that we’re doing. We want to apply our findings in ways that won’t cause more disparities, won’t cause stigmatization. There are human beings behind each of the numbers in a study.’” Finding factors that place Black people at risk Meanwhile, Hudson, a social scientist, and Babulal, a health science researcher, are taking a multidisciplinary and multidimensional approach to studying the factors that put Black people at risk of Alzheimer’s disease. Their study blends cutting-edge biomedical research with community-engaged research to investigate how mental health and other factors influence overall health and affect the risk of cognitive decline among Black Americans. The study will use the NIA Health Disparities Research Framework to guide assessment of the environmental, sociocultural, behavioral and biological factors at play. Their study is known as ARCHES, for Aging Research Characterizing Health Equity via Social determinants. The researchers are recruiting a diverse group of 300 Black St. Louisans to represent a wide range of life experiences among people in the Black community. To recruit such a large and diverse participant group, the researchers have set up a community advisory board and partnered with community organizations to help develop communication messages and design strategies for reaching people from a variety of geographic and sociodemographic backgrounds. Hudson “There&＃8217;s a lot of heterogeneity within the Black American population socioeconomically, geographically, in experiences and so on,” Hudson said. “Throughout St. Louis and other communities like it, people live in essentially separate and not equal social and physical environments, and that cascades across the life course, leading to premature death and many different illnesses. We think it&＃8217;s important to obtain a truly representative sample to investigate how these physical and social environmental factors can affect Black Americans and their risk of Alzheimer&＃8217;s disease.” Hudson and Babulal are investigating how factors such as depression, stress, access to health care, experience with discrimination, and employment affect cognitive function and molecular biomarkers of Alzheimer’s disease. The results could yield insight into the roots of Black Americans’ elevated risk for the disease and potentially identify new strategies to reduce that risk. Babulal “We don’t have a full view of how all these factors impact health and aging in America,” Babulal said. “We know social experiences affect the body, but we’re still working out how, exactly, environment and health behaviors interact with biology to influence the risk of cognitive impairment. We need to know the causal mechanisms so we can find ways to intervene and reduce these health inequities that have been present for decades and longer.” Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on Pinterest (Opens in new window)Click to share on LinkedIn (Opens in new window) The COEQUAL registry is supported by NIH grant number R24AG074915. The ARCHES study is supported by NIH grant number R01AG074302. Media Contact Judy Martin FinchDirector of Media Relationsm: [email protected] Writer Tamara BhandariSenior Medical Science [email protected] Tamara covers infectious diseases, molecular microbiology, neurology, neuroscience, surgery, the Institute for Informatics, the Division of Physician-Scientists and the MSTP program. She holds a double bachelor's degree in molecular biophysics & biochemistry and in sociology from Yale University, a master's in public health from the University of California, Berkeley, and a PhD in biomedical science from the University of California, San Diego. She joined WashU Medicine Marketing & Communications in 2016. She has received three Robert G. Fenley writing awards from the American Association of Medical Colleges: a bronze in 2020 for "Mind’s quality control center found in long-ignored brain area," a silver in 2022 for "Mice with hallucination-like behaviors reveal insight into psychotic illness," and a bronze in 2023 for "Race of people given Alzheimer’s blood tests may affect interpretation of results." Since January of 2024, Tamara has been writing under the name Tamara Schneider. Related Editors' Picks June 6, 2024 Uncovering ‘the basis of humanity’ one puzzle at a timeMD/PhD student creates crosswords for major newspapers.Medical Campus & Community, Profiles May 30, 2024 Risk of death from COVID-19 lessens, but infection still can cause issues 3 years laterStudy also shows that patients hospitalized within 30 days after infection face 29% higher death risk in 3rd year compared with those not infected.News Release May 17, 2024 Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other virusesResponse to updated vaccine is shaped by earlier vaccines yet generates broadly neutralizing antibodies.News Release Directories Maps &＃038; Directions Calendars Contact Giving Follow us on Facebook Follow us on Twitter Follow us on Instagram Subscribe to us on YouTube Follow us on LinkedIn Follow us on TikTok Washington University School of Medicine 660 S. Euclid Ave., St. Louis, MO 63110-1010 Consistently ranked a top medical school for research, Washington University School of Medicine is also a catalyst in the St. Louis biotech and startup scene. Our community includes recognized innovators in science, medical education, health care policy and global health. We treat our patients and train new leaders in medicine at Barnes-Jewish and St. Louis Children's hospitals, both ranked among the nation's best hospitals and recognized for excellence in care. Departments & Programs A to Z Index Announcements Outlook Magazine Report Website Issue Emergency Policies News © 2024 Washington University in St. Louis   Loading Comments...   Write a Comment... Email (Required) Name (Required) Website