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Skip to content Skip to search Skip to footer Neurosurgery Open Menu Back Close Menu Search for: Search Close Search AboutAbout News Diversity, Equity & Inclusion Contact Us Giving PeoplePeople Clinical Faculty Research Faculty Affiliated Faculty Fellows Residents Advanced Practice Providers Administration Patient CarePatient Care Aneurysms/Vascular Brain Tumors Chiari Malformation / Syringomyelia Epilepsy Hydrocephalus Movement Disorders Pain Pediatrics Peripheral Nerve Spine ResearchResearch Laboratories Clinical TrialsClinical Trials Trials with Outpatient EnrollmentTrials with Outpatient Enrollment Outpatient – Pediatric Outpatient-Spine and Peripheral Nerve Outpatient – Epilepsy and Functional Outpatient-Vascular Outpatient-Oncology Trials with Inpatient EnrollmentTrials with Inpatient Enrollment Inpatient – Oncology Inpatient – Vascular Inpatient- Pediatric Inpatient-Spine and Peripheral Nerve NeurotechnologyNeurotechnology Center for Innovation in Neuroscience and Technology (CINT) NEURO360 EducationEducation Residency Program Fellowship ProgramsFellowship Programs Advanced Surgical Neuro-oncology Fellowship Endovascular Surgical Neuroradiology Fellowship Pediatric Neurosurgery Fellowship Neurosurgical Peripheral Nerve and Spine Fellowship Neurosurgical Complex Spine Fellowship Stereotactic, Functional and Epilepsy Surgery Fellowship Third-year Clerkship Diversity Sub-internship Funding Medical Student Research Opportunities Fourth-year Sub-internship Learning Environment Life Outside the Hospital Join Our Team AppointmentsAppointments Patient imaging Patient forms Open Search Outpatient – Pediatric General Pediatric Neurosurgery PI: Haller Protocol ID: 201904099-1001 Short study title: Genetics of Chiari Malformation Short description: The purpose of this study is to perform genetic testing on patients and their relatives with Chiari I malformations in order to understand disease progression, disease biology, and help to develop newer therapies. Key eligibility criteria: Any sex, any age Patients with a diagnosis of Chiari I malformation (with and without syringomyelia), defined as >= 5mm tonsillar herniation on radiological imaging or report Biological relatives of patients with Chiari I malformation Participants willing to undergo genetic testing which includes any or all of the following: blood, saliva, urine, cheek swab, other tissue See if you qualify for the Chiari Genetics Project by clicking here. Contact person: Hilda Mata, 314-454-4113, [email protected] Enrollment period: Current PI: Roland Protocol ID: 201906065 Short study title: Advanced Imaging of Chiari Malformation Short description: While structural MRI is useful in the diagnosis and workup of Chiari malformation, advanced imaging may offer additional information previously not recognized by traditional imaging methods. The purpose of this study is to use advanced MRI techniques, pioneered by Washington University, to assess the relationship between structure and function of brain structures in Chiari malformation. These techniques include diffusion scans and resting state functional MRI. These methods might allow better understanding of the development of symptoms, syringomyelia, and other pathologies of the craniocervical junction. Key eligibility criteria: Any sex, any age Patients with a diagnosis of Chiari I malformation (with and without syringomyelia), defined as >= 5mm tonsillar herniation on radiological imaging or report Participants undergoing un-sedated MRI scan ordered for clinical purposes and are willing to undergo an additional 15 minutes of scanning Learn more about current projects through the Parks-Reeves Consortium here. Contact person: Ashley Roberts, 314-454-2881, [email protected] Enrollment period: Current PI: Strahle Protocol ID: 201011724 Short study title: The Park-Reeves Syringomyelia Research Consortium This study is closed for enrollment. Applications for data can be requested here.  Contact person: Thanda Meehan, 314-454-3212, [email protected] Enrollment period: Closed Pediatric Hydrocephalus PI: Limbrick Protocol ID: 201511126 Short study title: Advanced MR Imaging in Congenital Hydrocephalus Short description: Washington University is a pioneer in developing advanced MR imaging techniques, which have helped to provide new insight into the brain’s structure and function. However, these techniques have rarely been used in pediatrics. Brain development and abnormalities associated with congenital diseases are largely unexplored in the setting of advanced MR imaging. The goal of this study is to use advanced MR imaging to better understand brain development in the setting of congenital hydrocephalus. Key eligibility criteria: Any sex, age 17 years and younger Diagnosis of congenital hydrocephalus Patient scheduled to undergo surgery for hydrocephalus and a clinically indicated MRI before treatment Patients able to undergo two sessions of an MRI (30 minutes each). The first session will be either in the same setting as the clinically indicated pre-operative MRI or in a separate setting. The second will be after the surgery and before hospital discharge. Sedation will not be used in research-only MRIs. Contact person: Diego Morales, 314-454-4688, [email protected] Pediatric Oncology PI: Limbrick Protocol ID: 202002124 Short study title: Pediatric Neurosurgery Tissue Bank Short description: The purpose of the Pediatric Neurosurgery Tissue Bank is to collect and store tissue samples from patients undergoing surgery. These samples include benign and malignant brain/spine tumors, normal/abnormal brain tissue, cerebrospinal fluid (CSF), bone, blood samples, and other related tissues. Specimens will be collected from the operating room or specialized procedure room in which said tissue is removed. Biological parents and siblings are also eligible to donate blood samples. Data from this tissue bank will be used to better understand disease progression, disease biology, generate realistic animal models of disease, and help to develop newer therapies. Key eligibility criteria: Any sex, any age Patients scheduled to undergo surgical resection for brain/spinal tumor, seizure focus, or brain malformation Biological parents and siblings are also eligible to donate blood samples Patients at end-of-life are eligible to participate through the Legacy Brain Donation Program Contact person: Diego Morales, 314-454-4688, [email protected] Enrollment period: Current Pediatric Epilepsy PI: Limbrick Protocol ID: 202002124 Short study title: MRI Predictors of Response to Vagal Nerve Stimulation Short description: Patients with medically refractory epilepsy may be candidates for vagal nerve stimulation (VNS), which are implanted devices that alter the brain’s excitability and thereby decrease seizure frequency. However, it is not clear which patients will respond well to vagal nerve stimulation and will have an improved quality of life after surgery. The aim of this study is to analyze brain MRI scans for patients before and after surgery and to collect information relating to seizure frequency and quality of life in order to better identify patients who might benefit from this treatment. Key eligibility criteria: Any sex, any age Patients undergoing VNS therapy Contact person: Diego Morales, 314-454-4688, [email protected] Enrollment period: Current Clinical Trials Trials with Inpatient Enrollment Trials with Outpatient Enrollment Outpatient-Oncology Outpatient-Vascular Outpatient-Spine and Peripheral Nerve Outpatient – Epilepsy and Functional Outpatient – Pediatric Department of NeurosurgeryWashington University School of Medicine660 South Euclid AvenueCampus Box 8057St. Louis, MO 63110314-362-3570Contact Us Instagram Twitter YouTube Information Refer a patient Clinical faculty directory Locations Giving Careers Faculty job openings Staff job openings Patients MyChart Patient forms Patient imaging ©2024 Washington University in St. Louis

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