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Skip to content Skip to search Skip to footer Neurosurgery Open Menu Back Close Menu Search for: Search Close Search AboutAbout News Diversity, Equity & Inclusion Contact Us Giving PeoplePeople Clinical Faculty Research Faculty Affiliated Faculty Fellows Residents Advanced Practice Providers Administration Patient CarePatient Care Aneurysms/Vascular Brain Tumors Chiari Malformation / Syringomyelia Epilepsy Hydrocephalus Movement Disorders Pain Pediatrics Peripheral Nerve Spine ResearchResearch Laboratories Clinical TrialsClinical Trials Trials with Outpatient EnrollmentTrials with Outpatient Enrollment Outpatient – Pediatric Outpatient-Spine and Peripheral Nerve Outpatient – Epilepsy and Functional Outpatient-Vascular Outpatient-Oncology Trials with Inpatient EnrollmentTrials with Inpatient Enrollment Inpatient – Oncology Inpatient – Vascular Inpatient- Pediatric Inpatient-Spine and Peripheral Nerve NeurotechnologyNeurotechnology Center for Innovation in Neuroscience and Technology (CINT) NEURO360 EducationEducation Residency Program Fellowship ProgramsFellowship Programs Advanced Surgical Neuro-oncology Fellowship Endovascular Surgical Neuroradiology Fellowship Pediatric Neurosurgery Fellowship Neurosurgical Peripheral Nerve and Spine Fellowship Neurosurgical Complex Spine Fellowship Stereotactic, Functional and Epilepsy Surgery Fellowship Third-year Clerkship Diversity Sub-internship Funding Medical Student Research Opportunities Fourth-year Sub-internship Learning Environment Life Outside the Hospital Join Our Team AppointmentsAppointments Patient imaging Patient forms Open Search Outpatient-Vascular PI: Osbun Short study title: Dural Arteriovenous Fistula Genetics Repository Short description: The aim of this study is to generate a biospecimen repository for the analysis for the genomic determinants of dural arteriovenous fistula pathophysiology. Consented patients will supply a saliva or blood sample which will be linked with clinical outcomes data. The long-term goal of this study is to provide information to help in future candidate gene studies, genome-wide association studies, and/or rare variant analyses. The information garnered may one day serve as biomarkers for patient risk-stratification into more or less aggressive medical therapy and monitoring groups and elucidate pathways to study and develop targeted therapeutic strategies. Key eligibility criteria: Diagnosis of dural arteriovenous fistulaAny sex, age 18 and upWillingness to provide blood sample (20-30cc) or saliva sample Contact person: Brigette Vaughn, 314-273-0368, [email protected] Enrollment period: January 30, 2020 – Current PI: Osbun Short study title: Patient-Centered Outcomes in Transradial and Transfemoral Cerebral Angiography Short description: Cerebral angiography is a mainstay for diagnosis and treatment of a variety of cerebrovascular diseases including aneurysms, stroke, and carotid stenosis. Traditionally, vascular access is obtained via the femoral artery in the groin, but more recent studies, especially in cardiology, have transitioned to using a less-invasive access via the radial artery in the wrist. These studies in cardiology have shown superiority of the transradial approach in patient safety, patient preference, and hospital costs, but these benefits are not known to translate to cerebral angiography. The aim of this study is to determine the cost of transradial and transfemoral cerebral angiography and to compare the patient-reported outcomes in both of these approaches. Key eligibility criteria: Any sex, age 18 and upPatient scheduled to undergo 4-vessel elective outpatient cerebral angiography for diagnostic purposesAbility to access computerized follow-up surveys from a computer or smartphone Patients will be recruited from the Neurosurgery and Interventional Neuroradiology outpatient clinics Enrollment period: February 2020 – Current PI: Osbun Short study title: Genomics and Biospecimen Repository for Patients with History of Ruptured Aneurysm Short description: Ruptured aneurysms leads to subarachnoid hemorrhage (SAH), a type of stroke that affects ~30,000 people per year in the US. It is associated with high mortality and can lead to permanent or significant loss of neurologic function. To date, it is not known whether there are potential gene mutations that are associated with this disease or treatment response. This study aims to collect, process, and bank biospecimens (blood and/or saliva) from patients who have had a history of a ruptured aneurysm(s). Patients who come to an outpatient clinic for follow-up of a ruptured aneurysm are eligible for this study. Key eligibility criteria: Any sex, age 18 and upConfirmed diagnosis of aneurysm and SAHAneurysm secured by coil or clip, treated at Barnes Jewish Hospital Contact person: Brigette Vaughn, 314-273-0368, [email protected] Enrollment period: October 2019 – current PI: Ray and Osbun Short study title: Wearable and Wireless Pressure Sensor for Monitoring Skin Pressure (Mercury Patch) Short description: Hospital-acquired pressure ulcers are preventable problems that carry significant morbidity despite close monitoring. These complications are more prevalent among patients with neurologic injury or paralysis. Our group and other have developed the Mercury Patch, a noninvasive, low-cost, wireless, flexible patch that contains pressure-sensing and transmitting features that could communicate information about continuous skin pressure. The goal of this study is to use the Mercury Patch to record sacral pressure during prolonged neurosurgical procedures and relate them to patient characteristics and outcomes such as pressure ulcer development and bladder/bowel incontinence. Key eligibility criteria: Age 18 and upPatients scheduled to undergo any cranial or skull base surgery lasting longer than four hours in duration and is able to follow up for 2-4 weeks after surgeryExcludes: patients with existing or prior sacral pressure ulcer, pre-existing impaired skin integrity, history of pilonidal cyst, cellulitis, psoriasis, or eczema, patients who are bedridden or have impaired mobility, BMI > 40, lower back tattoos, allergy to silicone adhesives or Tegaderm Contact person: Linda Koester, 314-362-7368, [email protected] Enrollment period: November 2021 – Current Clinical Trials Trials with Inpatient Enrollment Trials with Outpatient Enrollment Outpatient-Oncology Outpatient-Vascular Outpatient-Spine and Peripheral Nerve Outpatient – Epilepsy and Functional Outpatient – Pediatric Department of NeurosurgeryWashington University School of Medicine660 South Euclid AvenueCampus Box 8057St. Louis, MO 63110314-362-3570Contact Us Instagram Twitter YouTube Information Refer a patient Clinical faculty directory Locations Giving Careers Faculty job openings Staff job openings Patients MyChart Patient forms Patient imaging ©2024 Washington University in St. Louis

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