博柏利18年新标|18luck新利体育app

Skip to content Skip to search Skip to footer Program in Physical Therapy Open Menu Back Close Menu Search for: Search Close Search EducationEducation Doctor of Physical TherapyDoctor of Physical Therapy Application &＃038; Admissions Eligibility &＃038; Prerequisites Tuition &＃038; Financial Assistance Educational Experience Student Activities Curriculum CAPTE Success Statistics Clinical Education Program Clinical Instructor Resources PhD in Movement SciencePhD in Movement Science Application &＃038; Admissions Curriculum &＃038; Degree Requirements Tuition &＃038; Financial Assistance Current PhD Students PhD Alumni Steering Committee Dual DPT-PhD Postdoctoral Research FellowshipPostdoctoral Research Fellowship Application &＃038; Admissions Current Postdoctoral Research Scholars Financial Assistance Clinical Residency in Orthopaedics Clinical Residency in Women’s HealthClinical Residency in Women’s Health Application &＃038; Admissions AlumniAlumni Open Positions The Next 75 Years WUPT 75th Anniversary Celebration Movement System Impairment Syndromes CoursesMovement System Impairment Syndromes Courses Movement System Impairment (MSI) Resources Continuing Education for Clinical Instructors (CEUs)Continuing Education for Clinical Instructors (CEUs) Research Seminars &＃038; Recordings Schedule a Student Visit Patient CarePatient Care LocationsLocations Central West End Danforth Campus O&＃8217;Fallon Our Providers Our ServicesOur Services Musculoskeletal Rehabilitation Neuromuscular Rehabilitation Multidisciplinary Services Women’s &＃038; Men’s Pelvic Rehabilitation Pre- &＃038; Post-Surgical Rehabilitation Sports Injury &＃038; Performance Programs Specialty Techniques Vestibular and Concussion Rehabilitation Specialty Services and Programs Lymphedema Management Spinal Cord Injury Rehabilitation Cerebral Palsy Rehabilitation Wheelchair Seating and Positioning Clinic Aphasia Treatment Stroke/CVA Rehabilitation Dysphagia Treatment Social Work/Clinical Case Management Traumatic Brain Injury Rehabilitation Return to Driving Running Clinic Rehabilitation of the Performing Artist LSVT Loud Injury Prevention Programs Parkinson’s Disease Rehabilitation ASTYM Obesity Management dorsaVi VitalStim Therapy Telehealth Billing &＃038; Insurance Patient Testimonials ResearchResearch Our Research AreasOur Research Areas Foot &＃038; Ankle Injury &＃038; Recovery Hardware &＃038; Software Design for Rehabilitation Research Integrative Muscle Physiology Exercise and Cardio-Metabolic Health Movement &＃038; Musculoskeletal Problems in Diabetes Movement &＃038; Neurodegenerative Disease Neural Control of Movement Following Neurological Injury Neural Plasticity and Sensorimotor Integration Nutrition &＃038; Exercise Science Prevention, Rehabilitation &＃038; Maintenance in Musculoskeletal Conditions Physical Activity &＃038; Fitness Rehabilitation Research for Orthopaedic Conditions Stroke Recovery, Rehabilitation, and AccelerometryStroke Recovery, Rehabilitation, and Accelerometry For Lab Members Orthopaedic Biomechanics Accelerometry Movement Science Research Center Research Training Programs Clinical Trials Recent Publications Faculty &＃038; StaffFaculty &＃038; Staff Faculty Staff Clinical Providers Faculty Emeritus Open Faculty Positions DiversityDiversity PTID City Faces Recruitment Organizations &＃038; Student Groups Diversity, Equity, and Inclusion Resources Calendar AboutAbout Annual ReportAnnual Report 2019 Annual Report – Welcome2019 Annual Report – Welcome 2019 Annual Report – Education 2019 Annual Report – Clinical Practice 2019 Annual Report – Research 2019 Annual Report – Community Explore the Program in Physical Therapy Moving Ahead ContactContact Maps &＃038; Directions Schedule a Student Visit Seminar Series Invitation Request Work at WashU PT WUSM Bike Run Walk Club WUPT at 2024 Combined Sections Meeting Open Search Neural Control of Movement Following Neurological Injury We investigate the ways in which the central nervous system controls movement through study of the motor unit: the key structure that transforms neural commands that converge upon it in the spinal cord into motor output through the generation of muscle force. Analysis of motor unit population discharge allows the study of voluntary motor commands at the end-stage of central nervous system processing. In this way, it captures contributions to motor processing not only from the brain, but also from the brainstem, spinal cord, and a-motoneuron—structures that are implicated after neurological injury but are often overlooked in human neurorehabilitation. We measure motor unit discharge non-invasively in humans using high-density surface EMG recordings (in up to six muscles simultaneously) coupled with an automatic decomposition algorithm (Negro et al., 2016). By performing various time- and frequency-domain analyses on the decomposed motor unit spike trains, we can “decode” information about the synaptic inputs that the motoneurons received and thereby characterize the voluntary motor command at the end-stage of central nervous system processing. This approach also allows us to record from many motor units simultaneously (rather than only a few), which is a major advantage because we can 1) extract much more detailed information about the characteristics of synaptic input to the motoneuron pool and 2) obtain robust population distributions from individuals in addition to group analyses. The recent development of this advanced technology enables us to address scientific and clinical research questions that were previously infeasible.  One line of research of our lab is to characterize pathological motoneuron discharge following injury to the central nervous system (e.g., stroke, multiple sclerosis) and to determine the ways in which it is associated with specific clinical motor deficits. These findings will identify which pathophysiological processes may be promising therapeutic targets and ascertain the therapeutic modalities that are most likely to be beneficial.  Our short-term goals are to quantify and characterize the ways in which neural drive to muscle is altered these conditions, and to evaluate the ways in which pathologic motor unit discharge is associated with typical motor deficits.  The long-term goals of our work are to increase patient function by (1) informing the development of targeted, personalized interventions, (2) by elucidating physiologic changes associated with current interventions, and (3) by providing sensitive disease monitoring tools. Another line of research in our lab is to study differences in neural control of proximal and distal muscles, which have different biomechanical functions and neural innervation patterns. This work provides foundational knowledge about function of the intact nervous system that is useful when seeking to understand why motor deficits following neurological injury often differ among proximal and distal muscles. We also collaborate with labs conducting pre-clinical research using animal paradigms (cat, rat, rabbit), which facilitate our ability to validate and interpret our findings from human experiments because the animal models provide a ground-truth measure of central nervous system output by permitting direct, invasive measurements from nervous system. Faculty Investigator Laura McPherson, PT, DPT, PhD [Profile ] Current Research Studies Factors influencing the detection of accurate and reliable motor unit population recordings in human participantsMcDonnell Center for Systems Neuroscience Small Project GrantPI: Laura McPherson CRCNS: Improving Bioelectronic Selectivity with Intrafascicular StimulationNIH/NIBIB R01EB027584PIs: Ranu Jung (Florida International University) and James Abbas (Arizona State University) Restorative Neuroplasticity in Brainstem Motor Pathways to Enhance Rehabilitation Post-StrokeAmerican Heart Association Innovative Project AwardPI: Jacob McPherson Research Our Research Areas Biostatistics, Evidence, and Research Design Foot &＃038; Ankle Injury &＃038; Recovery Integrative Muscle Physiology Movement &＃038; Neurodegenerative Disease Neural Control of Movement Following Neurological Injury Neural Plasticity and Sensorimotor Integration Orthopaedic Biomechanics Prevention, Rehabilitation &＃038; Maintenance in Musculoskeletal Conditions Rehabilitation Research for Orthopaedic Conditions Shoulder Biomechanics and Rehabilitation Stroke Recovery, Rehabilitation, and Accelerometry Tendon Rehabilitation Lab Movement Science Research Center Research Training Programs Clinical Trials Recent Publications Program in Physical TherapyMailing Address:Campus Box 8502, 4444 Forest Park Ave., Suite 1101St. Louis, MO 63108-2212314-286-1400Contact us Facebook Instagram Twitter YouTube For Patients Central West End &＃8211; @4240 4240 Duncan Ave., Suite 120 St. Louis, MO 63110 Central West End &＃8211; 4444 4444 Forest Park Ave., Suite 1210 St. Louis, MO 63108-2212 For patient appointments, call 314-286-1940   O&＃8217;Fallon 1 Progress Point Parkway O&＃8217;Fallon, MO 63368 Danforth Campus Zetcher House 6614 Shepley Dr., Suite 1051 Clayton, MO 63105   Resources Alumni Disclosures Maps & Directions ©2024 Washington University in St. Louis